Hideyo Sato Selected Research

Antiporters

1/2022	Lifespan extension with preservation of hippocampal function in aged system xc--deficient male mice.
1/2021	Aged xCT-Deficient Mice Are Less Susceptible for Lactacystin-, but Not 1-Methyl-4-Phenyl-1,2,3,6- Tetrahydropyridine-, Induced Degeneration of the Nigrostriatal Pathway.
1/2021	Chronic Sulfasalazine Treatment in Mice Induces System xc - - Independent Adverse Effects.
1/2021	Sorafenib fails to trigger ferroptosis across a wide range of cancer cell lines.
12/2020	Loss of the cystine/glutamate antiporter in melanoma abrogates tumor metastasis and markedly increases survival rates of mice.
1/2019	Anticonvulsant and antiepileptogenic effects of system xc- inactivation in chronic epilepsy models.
1/2015	System xC- is a mediator of microglial function and its deletion slows symptoms in amyotrophic lateral sclerosis mice.
10/2008	Time-dependent changes in striatal xCT protein expression in hemi-Parkinson rats.

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Hideyo Sato Research Topics

Disease

5	Neoplasms (Cancer) 01/2021 - 09/2014
5	Parkinson Disease (Parkinson's Disease) 01/2021 - 10/2008
3	Nervous System Diseases (Neurological Disorders) 01/2022 - 01/2021
3	Neuroinflammatory Diseases 01/2022 - 01/2019
3	Hepatocellular Carcinoma (Hepatoma) 01/2021 - 11/2019
3	Seizures (Absence Seizure) 01/2019 - 04/2011
2	Starvation 01/2021 - 01/2018
2	Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease) 11/2019 - 01/2015
2	Infections 01/2019 - 04/2007
2	Carcinoma (Carcinomatosis) 07/2015 - 09/2014
1	Hypothermia 01/2022
1	Renal Cell Carcinoma (Grawitz Tumor) 01/2021
1	Melanoma (Melanoma, Malignant) 12/2020
1	Neoplasm Metastasis (Metastasis) 12/2020
1	Ischemic Stroke 11/2019
1	Status Epilepticus (Complex Partial Status Epilepticus) 01/2019
1	Gliosis 01/2019
1	Epilepsy (Aura) 01/2019
1	Brain Injuries (Brain Injury) 01/2019
1	Encephalitis (Encephalitis, Rasmussen) 01/2018
1	Inflammation (Inflammations) 01/2018
1	Experimental Autoimmune Encephalomyelitis (Encephalomyelitis, Autoimmune Experimental) 01/2017
1	Parkinsonian Disorders (Parkinsonism) 01/2017
1	Disease Progression 01/2017
1	Demyelinating Diseases (Demyelinating Disease) 01/2017
1	Mood Disorders (Mood Disorder) 06/2015
1	Urinary Bladder Neoplasms (Bladder Cancer) 09/2014
1	Memory Disorders (Memory Loss) 04/2011
1	Atrophy 04/2011
1	Ischemia 10/2009
1	Acute Kidney Injury (Acute Renal Failure) 10/2009
1	Insulin Resistance 05/2009
1	Fatty Liver 05/2009
1	Endotoxemia 09/2007

Drug/Important Bio-Agent (IBA)

13	Cystine (L-Cystine)IBA 01/2022 - 09/2007
12	Glutamic Acid (Glutamate)FDA Link 01/2022 - 10/2008
8	AntiportersIBA 01/2022 - 10/2008
3	erastinIBA 01/2021 - 01/2018
3	Glutathione (Reduced Glutathione)IBA 01/2018 - 04/2011
2	CytokinesIBA 01/2022 - 01/2018
2	Sulfasalazine (Azulfidine)FDA LinkGeneric 01/2021 - 01/2019
2	Cysteine (L-Cysteine)FDA Link 01/2021 - 01/2018
2	lactacystinIBA 01/2021 - 01/2017
2	Proteins (Proteins, Gene)FDA Link 01/2019 - 01/2017
2	Anticonvulsants (Antiepileptic Drugs)IBA 01/2019 - 01/2017
2	LipopolysaccharidesIBA 01/2018 - 09/2007
2	Proteasome Endopeptidase Complex (Proteasome)IBA 07/2015 - 09/2014
1	Electron Transport Complex III (Coenzyme Q-Cytochrome-c Reductase)IBA 01/2021
1	Superoxides (Superoxide)IBA 01/2021
1	1- Methyl- 4- phenyl- 1,2,3,6- tetrahydropyridine (MPTP)IBA 01/2021
1	IronIBA 01/2021
1	Sorafenib (BAY 43-9006)FDA Link 01/2021
1	Protein Kinase InhibitorsIBA 01/2021
1	Phospholipid Hydroperoxide Glutathione PeroxidaseIBA 01/2021
1	Culture MediaIBA 01/2021
1	Pharmaceutical PreparationsIBA 12/2020
1	EdaravoneIBA 11/2019
1	Free Radical ScavengersIBA 11/2019
1	Pilocarpine (Ocusert)FDA LinkGeneric 01/2019
1	Cisplatin (Platino)FDA LinkGeneric 01/2018
1	EndotoxinsIBA 01/2018
1	Zonisamide (Zonegran)FDA LinkGeneric 01/2017
1	Proteasome InhibitorsIBA 09/2014
1	Acetylcysteine (Siran)FDA LinkGeneric 04/2011
1	Urea (Carbamide)FDA LinkGeneric 10/2009
1	NitrogenIBA 10/2009
1	CreatinineIBA 10/2009
1	salicylhydroxamic acid (SHAM)IBA 10/2009
1	TransferasesIBA 05/2009
1	GlucokinaseIBA 05/2009
1	2- cyclohexylidenhydrazo- 4- phenyl- thiazoleIBA 05/2009
1	Insulin (Novolin)FDA Link 05/2009
1	Carnitine (L-Carnitine)FDA LinkGeneric 05/2009
1	AcidsIBA 05/2009
1	AntibodiesIBA 10/2008
1	Messenger RNA (mRNA)IBA 09/2007
1	Amino Acid Transport System X-AG (Glutamate Transporter)IBA 09/2007
1	Reactive Oxygen Species (Oxygen Radicals)IBA 04/2007

Therapy/Procedure

1	Subcutaneous Injections 12/2020
1	Therapeutics 01/2019
1	Electrodes (Electrode) 01/2019
1	Injections 01/2018
1	Nephrectomy 10/2009